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Making the pieces fit: How WVU, Marshall and the state of West Virginia detect new COVID-19 variants

Picture viral RNA as a single component that you can break into one million pieces. Now imagine reassembling those pieces together, literally like a jigsaw puzzle. If there’s a chipped corner or if a piece won’t fit snugly as it should, consider that a virus mutation or variant. That’s genomic sequencing, in a nutshell, when it comes to identifying variants of COVID-19, according to Peter Stoilov, associate professor of biochemistry at the West Virginia University School of Medicine. Stoilov helps lead the laboratory efforts of a statewide partnership between WVU Medicine, Marshall University and the state Department of Health and Human Resources to identify SARS-CoV-2 variants.