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Like night and day: Animal studies may not translate to humans if time of day is disregarded

Imagine being woken up at 3 a.m. to navigate a corn maze, memorize 20 items on a shopping list or pass your driver’s test. According to a new analysis out of West Virginia University, that’s often what it’s like to be a rodent in a biomedical study. Mice and rats, which make up the vast majority of animal models, are nocturnal. Yet a survey of animal studies across eight behavioral neuroscience domains showed that most behavioral testing is conducted during the day, when the rodents would normally be at rest.

Why We Should All Choose Vaccination

The COVID-19 pandemic has decreased markedly in numbers of new cases, hospitalizations and deaths in West Virginia and in the United States. However, when carefully looking at the data, it is evident that the impact of reduced COVID-19 infections, hospitalizations and deaths are largely in our residents who are fully vaccinated.